Serzone News

Serzone Liver Failure Warning

The FDA has requested that Bristol-Myers Squibb Co. add a black box warning to its antidepressant Serzone. Serzone has been linked to liver failure, which may require a transplant or cause death. A similar warning was issued by the Canadian government last summer. Click here for more...

Study Indicates Liver Failure in Patients Taking Nefazodone

Research has indicated that liver failure can occur in patients taking nefazodone, also known as Serzone. In one study conducted in 1999, researchers documented three cases of liver failure in patients taking the medication. The first patient was a 54-year-old woman who had to undergo a liver transplant but died soon after. The second patient was a 16-year-old girl who had to undergo a liver transplant and survived the operation. The third patient was a 57-year-old woman whose condition improved after she was taken off Serzone. These cases led researchers to recommend that patients undergoing therapy should have regular liver toxicity tests and that patients with liver disease should not take the drug. Click here for more...

Serzone Lawsuit

In 1997, a 15-year-old Ohio girl suffered liver failure as a result of taking the prescription antidepressant Serzone. The drug is not approved for use in adolescents or teenagers, but the FDA was aware that it would be prescribed in an "off label" manner to this group. The Ohio girl had to undergo a liver transplant and has been hospitalized at least twice since that time. The girl's parents have filed a lawsuit against the maker of Serzone, the psychiatrist who prescribed the drug, and the hospital where the girl was treated. Click here for more...

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